• Assistant Professor, Human Biology Division, Fred Hutch Cancer Center

Fred Hutch Cancer Center 

Hutchinson Building

1100 Fairview Ave. N.

Mail Stop C1-015

Seattle, WA 98109

Phone Number: 
(206) 667-3449
Email: 
jmayers@fredhutch.org
Fred Hutch Cancer Center Profile Mayers Lab
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Biography 

Dr. Jared Mayers is a physician-scientist who treats cancer patients’ preexisting pulmonary conditions and pulmonary complications from cancer treatment while running a research laboratory at Fred Hutch. He studies the role of microbes in bloodstream infections, cancer and other diseases. Through these studies, he aims to understand the metabolism of harmful microbes in their natural context with the goal of harnessing his lab’s discoveries for clinical benefit. His techniques draw on clinical sample data and use multi-omics, biochemistry, microbiology and mouse models to investigate microbial contributions to these diseases.

Education 
  • MD, Harvard Medical School, 2017
  • PhD (Biology), Massachusetts Institute of Technology, 2015
Health Topics 
  • Anti-Microbial Resistance (AMR)
Publications 
  1. Mayers JR, Varon J, Zhou RR, Daniel-Ivad M, Beaulieu C, Bhosle A, Glasser NR, Lichtenauer FM, Ng J, Vera MP, Huttenhower C, Perrella MA, Clish CB, Zhao SD, Baron RM, Balskus EP. A metabolomics pipeline highlights microbial metabolism in bloodstream infections. Cell. 2024 Jul 25;187(15):4095-4112.e21. doi: 10.1016/j.cell.2024.05.035. Epub 2024 Jun 16. PubMed PMID: 38885650; PubMed Central PMCID: PMC11283678. 
  2. Rogers RS, Sharma R, Shah HB, Skinner OS, Guo XA, Panda A, Gupta R, Durham TJ, Shaughnessy KB, Mayers JR, Hibbert KA, Baron RM, Thompson BT, Mootha VK. Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock. Metabolomics. 2024 Mar 6;20(2):36. doi: 10.1007/s11306-024-02089-z. PubMed PMID: 38446263; PubMed Central PMCID: PMC10917846.
  3. Choi B, San José Estépar R, Godbole S, Curtis JL, Wang JM, San José Estépar R, Rosas IO, Mayers JR, Hobbs BD, Hersh CP, Ash SY, Han MK, Bowler RP, Stringer KA, Washko GR, Labaki WW. Plasma metabolomics and quantitative interstitial abnormalities in ever-smokers. Respir Res. 2023 Nov 4;24(1):265. doi: 10.1186/s12931-023-02576-2. PubMed PMID: 37925418; PubMed Central PMCID: PMC10625195.
  4. Mayers JR, Varon J, Zhou RR, Daniel-Ivad M, Beaulieu C, Bholse A, Glasser NR, Lichtenauer FM, Ng J, Vera MP, Huttenhower C, Perrella MA, Clish CB, Zhao SD, Baron RM, Balskus EP. Identification and targeting of microbial putrescine acetylation in bloodstream infections. bioRxiv.2023 Sep 21;. doi: 10.1101/2023.09.21.558834. PubMed PMID: 37790300; PubMed Central PMCID: PMC10542159.

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