Projects

• A Longitudinal Dissection of the Immune Response during Lyme Disease
• Leadership operations center for HIV Vaccine Trials Network
• Role of Proviral Loci in HIV Latency
• TeleDOT - Video-Assisted Directly Observed Therapy
• The Seattle Flu Study (SFS) and the Seattle Coronavirus Assessment Network (SCAN)
• 3D human-based microvessel bed for the study of Plasmodium falciparum interacting with vessel wall
• A chemical proteomics survey of Plasmodium gametocyte development
• A Comprehensive Assessment of HIV Drug Resistance Among Seroconverters using Tenofovir Disoproxil Fumarate (TDF)- Containing Pre-Exposure Prophylaxis (PrEP) in Kenya
• A Demonstration Project of Truvada Based Pre-exposure Prophylaxis (PrEP) to Prevent HIV Infection in Female Sex Workers
• A differentiated care model to improve the efficiency of PrEP delivery in Kenya
• A Multi-Country Prospective Evaluation of the Global Fund Business Model
• A rapid point-of-care test to improve PrEP adherence
• A specialist-generalist frame-work for viral transmission in salmon of the Northwest
• A Study to Assess the Efficacy of a Heterologous Prime/Boost Vaccine Regimen of Ad26.Mos4.HIV and Aluminum Phosphate-Adjuvanted Clade C gp140 in Preventing Human Immunodeficiency Virus (HIV) -1 Infection in Women in Sub-Saharan Africa
• Acceptability of Sustained-Release Antiretrovirals for Treatment in the US and sub-Saharan Africa
• ACCHIVe – The Cervical Cancer Prevention and Care Cascade
• Adhesive Interactions in Severe Malaria
• Adolescent Health Scientific Working Group
• Adolescent Transition to Adult Care for Adolescents living with HIV in Kenya (ATTACH)
• Advancing point-of-care diagnostics for integrated HIV and TB care in South Africa
• Advancing STI control and prevention through new innovations for STI testing technology: Integrated Point-Of-Care Testing (POCT)
• Afrocentric Precision Approach to Control Health Epidemics (APACHE)
• Antimicrobial resistance patterns of Salmonella and Shigella
• Antivirals for Biodefense
• Arginine sensing in Leishmania and its role in virulence
• Assisted Partner Notification to Augment HIV Treatment and Prevention in Kenya
• Assisted partner services and phylogenetics for HIV and hepatitis C prevention (SHARP)
• Association between schistosomiasis infection and HIV-1 acquisition, transmission and disease progression in Africa
• Atencion Primaria en Salud Nicaragua (APS) | Primary Health Care Nicaragua
• Azithromycin to prevent post-discharge morbidity and mortality in Kenyan children (Toto Bora Trial)
• Biological Determinants of Natural History of AIDS-Defining Cancers
• Biomarkers and interventions to prevent preterm birth and stillbirth associated with placental malaria
• BREATHE II
• CAPRISA Centre of Excellence in HIV prevention
• Caribbean Quality Improvement Collaborative
• Center for Emerging and Re-emerging Infectious Diseases
• Center for Structural Genomics of Infectious Diseases
• Center for the Study of Immune Mechanisms of Virus Control
• Center of Excellence, Peru: "Centro de Investigaciones Tecnológicas, Biomédicas y Medio Ambientales" (CITBM)
• CFAR: Implementation Science Core
• Childhood Acute Illness & Nutrition Network (CHAIN)
• Childhood Acute Illness and Nutrition Network
• Chlamydia Pneumoniae Persistence in the Blood Vessel
• Chlamydia Virulence: Exploitation of Host N-Glycosylation
• Chronic Inflammation and Early Risk of Atherosclerosis among HIV-infected Adults in Kenya
• Clinical and Public Health Curriculum Development, Training and Information Systems Support for the Haiti Health Care System
• Clinical Mentoring - onsite and via HIV ECHO
• Community-based Distribution Channels to Optimize Adolescent HIV Self-testing in Nairobi, Kenya
• Consortia for HIV/AIDS Vaccine Development
• Continuing Technical Assistance to Gavi-eligible Countries for HPV Vaccine Introduction
• Continuous Medical Education, Distance Learning, and Consultation Warmline
• Data Informed Stepped Care (DISC) to Improve Adolescent HIV Outcomes
• DC/PEPFAR Achieving HIV Epidemic Control through Scaling up Quality Testing, Care and Treatment in Malawi under the President’s Plan for AIDS Relief (PEPFAR)
• Defining BCR evolution during Immunization
• Defining Critical Events in Early HIV Infection: Effects of Alcohol & Early ART
• Defining HIV reservoirs that rebound following suspension of ART
• Defining the Role of Maternal Cells in Fetal and Infant Immunity to Malaria
• Delivering PrEP in Maternal Child Health (MCH) and Family Planning (FP) Systems
• Delivering PrEP in Pregnancy
• Delivering PrEP in pregnancy (PrIMA)
• Delivery of integrated PrEP and ART for HIV prevention for couples in Kenya
• Design and Delivery of Combination HIV Prevention in Young South African Women
• Design and Testing of Novel Vaccines Against Epstein-Barr Virus
• Designing an Intervention to Increase Men's Linkage to Care and Prevention after HIV Self-Testing in Uganda
• Determinants of outcome and recurrent infections in melioidosis
• Developing a Regional Interfaith Government Partnership
• Developing and Evaluating a Provider-delivered, National EMR Alert-based HIV ART Adherence Counseling Program in Haiti: iSanté Plus
• Developing Immunotherapy Approaches to Target Surface Proteins on Virally Infected Cancer Cells
• Developing Novel HIV-1 Vaccine Immunogens
• Developing the use of prevention cascade frameworks to improve management of HIV prevention programs
• Development and Clinical Evaluation of a Lyophilized Thermostable Tuberculosis Vaccine containing Adjuvant
• Development and implementaion of index testing model in I-TECH supported ART sites of Ukraine
• Development of a Novel Innate Immune Adjuvant System for Emerging RNA Virus Vaccines
• Development of a pre-erythrocytic P. vivax vaccine to prevent clinical relapse
• Development of Exploratory Operations Research to Decrease Loss-to-Follow-up of HIV+ Pregnant Women
• Development of routine monitoring and surveillance methods for progress towards elimination of mother to child transmission of HIV
• Development of Tuberculosis Vaccine Formulations
• DeWorm3
• Discovery of Chlamydia-host interactions
• DMPA use and vaginal bacterial diversity among African women
• DO ART: Delivery Optimization of ART
• Do lottery incentive strategies increase engagement in HIV care and uptake of antiretroviral therapy among South African men?
• DROP-TB: Diagnostic routines in HIV+ outpatients with tuberculosis
• Drug Resistance Genotypic and Phenotypic Correlates of Efavirenz and Dolutegravir based Treatment Outcomes across Non-B HIV-1 subtypes
• Dual Use Therapeutics for Cryptosporidiosis, Toxoplasmosis, and Neosporosis
• Dynamics of tuberculosis immune response in peripartum HIV-infected and HIV-uninfected women
• Early Infection in Women Exposed Mucosally to HIV-1
• Ebola viral disease preparedness and response activities
• Effect of whole genome methylation on HIV disease
• Effects of Contraceptives on Genital Immunity and HIV Susceptibility
• Electrokinetic paper diagnostic platform: 15-minute, quantitative nucleic acid amplification for viral pathogens in whole blood
• Eliciting VRC01-like bNAbs by Specifically Designed Env Immunogens
• End-term Evaluation (ETE) of USAID HIV Clinical Services Project (UTAP)
• Enhancing Enrollment and Retention in US Phase II Clinical Trials: AMP Behavioral Project
• Enterovirus in China
• eRX: A socio-technical systems approach for improving tuberculosis diagnosis using mobile health technologies
• Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED)
• Evaluating the relationship of CD101 and UBE2V1 to genital mucosal inflammation
• Evaluation of an intravaginal ring for HIV and pregnancy prevention with scientific partnerships and robust systems to strengthen HIV research in Western Kenya
• Evaluation of impact of an HIV/AIDS warm line for Mozambican clinicians engaged in HIV/AIDS care.
• Evaluation of Option B+ in Kenya
• Evaluation of the Coptic Hospital / University of Washington Collaborative HIV-1 Care Program - Kenya
• Examination of the Immune Response to Mycobacteria
• Expansion of Index Case Strategy to increase HIV+ case finding and improve continuum of care
• Exploring social norms driving mothers and caregivers' behaviors towards immunization in Cote d'Ivoire
• First-in-human clinical validation and feasibility of the Salus urine LAM assay for diagnosing active tuberculosis in South Africa
• First-line antimicrobials in children with severe acute malnutrition (FLACSAM)
• Functional genomics for Chlamydia
• GAPPS Repository
• Geospatial analyses of pneumonia, diarrhea, malaria, HIV/AIDS, tuberculosis and selected eradicable neglected tropical diseases
• Global Health Security Cooperative Agreement: Kenya
• GO-ED
• Harnessing Oral Mucosa Vaccination to Drive Protective HIV Antibody Responses
• Health law and policy technical assistance to National Department of Health of South Africa
• Health-Professional Education Partnership Initiative
• Hepatitis C testing and Mother to child transmission
• High-Sensitivity Lateral Flow Rapid Protein-Binding Assays for Pathogens
• High-Yield HIV Testing, Facilitated Linkage to Care, and Prevention for Female Youth in Kenya ‘GIRLS Study’
• HIV and Child Neurodevelopment in Kenya
• HIV integration-mediated modulation of immune regulation in HPV-associated cancers
• HIV Prevention Trials Network
• HIV self-testing and PrEP to increase testing and prevention uptake among male partners and improve postpartum ART use in PMTCT B+ programs in Uganda
• HIV self-testing to improve efficiency of PrEP delivery
• HIV Self-Testing, STI Self-Sampling and PrEP for Transgender Women in Uganda
• HIV Vaccine Trials Network (HVTN)
• HIV-specific target capture and quantitative isothermal amplification for acute HIV diagnosis and treatment monitoring
• HIVAcute and HIVAlert
• HPV Study: High Risk Women
• HPV type-specific prevalence and pregnancy and infant outcomes in HIV-positive women in Kenya
• Human African Trypanosomiasis (HAT) Elimination Initiative
• HVTN 703/HPTN 081: A phase 2b study to evaluate the safety and efficacy of VRC01 broadly neutralizing monoclonal antibody in reducing acquisition of HIV-1 infection
• I-TECH Botswana
• I-TECH Haiti/Centre Haïtien pour le Renforcement du Système de Santé (CHARESS)
• I-TECH India PLC
• I-TECH Kenya
• I-TECH Malawi
• I-TECH Mozambique
• I-TECH Namibia
• I-TECH South Africa
• I-TECH Tanzania
• I-TECH Technical Assistance to China
• I-TECH Technical Assistance to the Government of Cambodia
• Identification and Analysis of HIV-specific Naive B cells in HIV-Unexposed Individuals for Candidate Vaccine Antigens
• Identification of drug-targetable IFN-stimulated genes mediating immune activation during ART-treated HIV-1 infection
• Identification of Novel Mucosal Immune Mechanisms Involved in Protection from HIV-1
• Immune Profile and Network Analysis of Malaria Infection and Vaccination
• Immune Responses to Malaria and HIV Infection and Immunization
• Immunodominant Viral Memory CD4 Epitopes of Biosecurity & Geriatric Medicine Concern
• Immunoprotective Properties of Tissue-resident Memory T Cells in Mice and Humans within Mucosal Sites
• Impact of a novel screening program to detect acute and prevalent HIV infection and reduce HIV transmission
• Impact of HIV, Immune Activation, and ART on Child Neurodevelopment in Kenya
• Impact of Methamphetamine Use on the HIV Nucleome in individuals on Antiretroviral Therapy
• Impact of periconceptual vaginal microbiota on women's risk of preterm birth
• IMPACTA PERU Clinical Trials Unit (CTU)
• Implementation and expansion of high quality, sustainable and comprehensive HIV prevention, care, and treatment to achieve 90-90-90 goals in Western Kenya
• Improved Management to Increase Survival and Growth in Young Children at High Risk of Diarrhea Associated Mortality
• Improving Diagnosis, Treatment & Detection of Drug Resistance in HIV-2 Infection
• Improving Linkage to HIV Care Following Provider Initiated Testing and Counseling
• Improving the HIV Care Cascade in Kenya through Implementation Science Training
• Improving the Quality, Safety, and Productivity of the National Voluntary Medical Male Circumcision (VMMC) Program
• Improving Vaccination Coverage for Pregnant Women and Children
• Incident HSV-2 and Genital Health in Kenyan adolescent girls: an Inception Cohort
• Indigenous HIV/AIDS Research Training Program-Lauhoe IHART²
• Infection Prevention and Control: Kenya
• Infection-blocking antibody targets for malaria
• Influence of Pentecostal Churches on HIV/AIDS Testing and Treatment Adherence
• Innate Immune Antivirals for Biodefense
• Innate immune control of West Nile virus
• Innovative Approaches to Syphilis Vaccine Design
• Integrated bio-social models for HIV epidemiology
• Integrated Infectious Disease Capacity-Building Evaluation
• Integrated PrEP and ART Delivered in Ugandan Public Health Clinics to Improve HIV and ART Outcomes for HIV Serodiscordant Couples
• International AIDS Education and Training Center (IAETC)
• International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group
• Jak-STAT Control of Zika Virus Induced Fetal Injury
• JAK-STAT Control of Zika Virus-Induced Fetal Injury
• Kinetics, evolution, and effector function of Fc repertoires during vaccination with native-like Env trimers
• Kuunika: Strengthening HIV Related Health Data Systems and their Use in Malawi
• Legal environment assessment for access to HIV/AIDS pre-exposure prophylaxis by young women and adolescent girls in Southern Africa
• Malaria and HIV Diseases Interactions in Pregnancy
• Malaria Evolution in South Asia
• Male urethritis: Novel etiologies and natural history
• Malnutrition-enteric Diseases (MAL-ED) Study
• Martin Delaney Cure Collaboratory - Cell and Gene Therapy for HIV Cure
• Maternal Immunization Pharmacovigilance in Low- and Middle-Income Countries
• Maternal Microchimerism and BCG-Specific Immunoregulation in HIV-exposed Infants
• Mechanisms controlling the persistence of infectious HIV reservoirs in children
• Mechanisms of Severe T-cell Mediated Drug Hypersensitivity in Man
• Microbicide Trials Network
• Microneedle Patch Research
• Mitochondrial DNA of Normal and Mutant Trypanosomes
• Modeling approaches to prioritize TB prevention among people living with HIV in Uganda
• Modeling the Evolutionary and Public Health Impacts of HIV Adaptation in Response to Vaccination
• Molecular epidemiology of HIV and HCV transmission among PWID in Nairobi, Kenya
• Monitoring the development of anti-Env Abs during HIV-infection
• Mortality trends in HIV-infected people receiving ART in urban Malawi
• Multiplexible Autonomous Disposable Nucleic Acid Amplification Test for Chlamydia and Gonorrhea: Addressing an Epidemic Threat to Readiness at the Point-of-Care
• National HIV Integrated Training Curriculum
• Neonatal sepsis, antibiotic susceptibility pattern and treatment outcomes
• Neutralizing and non-neutralizing antibody effector functions in HIV infected children
• Next generation real-time monitoring for PrEP adherence in young Kenyan women
• Next generation real-time monitoring for PrEP adherence in young Kenyan women
• NIAID Centers of Excellence for Influenza Research and Surveillance
• NIH/NIAID Mucosal CTL Induction After HIV Exposure and Vaccination
• Novel Therapeutics for Class B Protozoa
• Nursing allocation strategies to deliver HIV services in priority public health settings
• OpCon Zambia - Adolescent Self Testing Project
• Optimal use of antibiotics in young children at high risk of diarrhea associated mortality.
• Optimizing repeat HIV testing during pregnancy and postpartum for PMTCT
• Oral home-based HIV testing for repeat maternal HIV testing in Kenya
• Oral swab diagnosis of HIV-TB
• Outbreak preparedness: Developing a pandemic risk map
• Overcoming Barriers to HIV/AIDS Care and ART Initiation
• Paracas: Program For Advanced Research Capacities For AIDS In Peru
• Pathogenesis and interventions for severe malaria
• Patient Centered Care
• PEPFAR Partnership Framework Policy Monitoring Project
• Persistence of CNS T. pallidum in HIV infection
• Pharmacy delivery to expand the reach of PrEP in Kenya
• Phosphosignaling in Mycobacterium tuberculosis
• Placental Colonization by Treponema Pallidum, Congenital Syphilis & Novel Vaccine Candidates
• Planning the MPACT trial – Mhealth strategies for the pediatric to adult HIV transition
• Point-of-care Urine Monitoring of Adherence (PUMA): Testing a Real-Time Urine Assay of Tenofovir in PrEP
• Post Treatment Control of HIV infection when treatment is started during primary infection.
• POWER: Scaleable, Effective Delivery of Microbicides and PrEP for Young Women in Kenya and South Africa
• Predicting PrEP Uptake and Adherence among Adolescent Girls and Young Women in Sub-Saharan Africa: Leveraging Programmatic and Clinical Trials Data
• PrEP and dPEP: Doxycycline post-exposure prophylaxis for prevention of sexually transmitted infections among Kenyan women using HIV pre-exposure prophylaxis
• Preparing for Scale-up of Differentiated HIV Service Delivery Models in Tanzania: Phase One Implementation
• Preventing Mycobacterium tuberculosis infection in HIV-exposed infants
• Prognostic Biomarkers in Critically Ill Individuals with Possible Life-Threatening Infections
• Promoting data quality improvement through the integration of HIS into workflows of nurses
• Prospective Evaluation of Novel Diagnostics for TB in KwaZulu-Natal, South Africa: The PROVE TB Study
• Pulmonary Defenses Against Intracellular Infection
• Quality Improvement for a Telephonic Clinical Consultation Service for HIV/AIDS Clinicians in Mozambique (the Linha Verde, or Warmline)
• Quality Improvement of Primary Health Care and HIV Services
• Rapid, Multiplexed Point-of-Care Molecular Detection of Respiratory Pathogens without Sample Prep
• Resistance to M. tuberculosis
• Respiratory infections in hospitalized adults
• Role of an ornithine rhamnolipid pigment in GBS virulence
• Role of human cervical mucus plugs in ascending GBS infection
• Role of the GBS hyaluronidase in regulation of immune responses during pregnancy
• Role of the microbiome in HIV vaccine induced heterogeneity
• Safety and Efficacy Study of Injectable Cabotegravir Compared to Daily Oral Tenofovir Disoproxil Fumarate/Emtricitabine, For Pre-Exposure Prophylaxis in HIV-Uninfected Cisgender Men and Transgender Women who have Sex with Men
• Scaling Up Voluntary Medical Male Circumcision (VMMC) to Prevent HIV Transmission in Zimbabwe
• Seattle Malaria Clinical Trials Center (MCTC)
• Securing Global Public Health through Strengthening Information Systems and Reporting in Kenya
• Serine hydrolase regulators of Mycobacterium tuberculosis non-replicating states
• Sexual Network analysis among transgender women (TGW)
• SHAMBA MAISHA: an agricultural intervention for food security and HIV health outcomes in Kenya
• Shikamana PrEP: A Community Participatory Approach to Integrating PrEP, Sexual Health, and Mental Health Services for GBMSM in Kenya
• Simulated patient encounters to promote early detection and engagement in HIV care for adolescents
• Social Frailty among Older Kenyan Women Living with and without HIV Infection
• Sofosbuvir Protection of the Fetal Brain from Zika Virus Infection in Pregnancy
• South Africa: Strengthening the Evidence Base and Capacity for Implementing HIV Prevention
• Spatial Epidemiology of HIV Transmission in High Burden Areas
• SPIRIT study: mapping structure, dynamics and behaviour of Dutch Caribbean HIV transmission networks to model targeted interventions
• Strengthening the Evidence Base and Capacity for Implementing HIV Prevention
• Strengthening the Health System Capacity to Implement HIV Prevention, Care, and Treatment Services in the Republic of South Africa
• Support laboratory management and laboratory workforce development to promote integrated, evidence-based HIV/ TB patient services in South Africa
• Support to the Mozambican Ministry of Health HIV ART Therapeutic Committees
• Supporting the Provision of Comprehensive HIV Testing, Treatment, Care, and Support Services in the Republic of Zimbabwe
• Surveillance of Antimicrobial Resistance in Neisseria gonorrhoeae
• Systematic Review of the Impact of HCV Infection on HIV Acquisition
• Systems Analysis and Improvement Approach to Optimize the Pediatric HIV Diagnosis and Care Cascade (SAIA-PEDS)
• Systems Analysis and Improvement to Optimize the Hypertension Treatment and Care Cascade for HIV-infected Individuals
• Systems Immunogenetics of Biodefense and Emerging Pathogens in the Collaborative Cross
• Systems Immunogenetics of Biodefense Pathogens in the Collaborative Cross
• T cell immune response to syphilis
• Targeted Long-acting Antiretroviral Therapy (TLC-ART)
• TB Epidemiologic Studies Consortium
• TB REACH Wave 6: Optimizing the DR TB Case Cascade in Mozambique
• Technical support in M&E of HIV clinical services
• Technology, Research, Education and Technical Assistance for Tuberculosis Project
• The CHIME Projects: PHASE, Option B+, Family Planning, & DART
• The effect of HIV exposure and infection on immunity to TB in children
• The Epidemiology of Extended Spectrum Beta Lactamase and Macrolide Resistance Genes in Kenyan Children Discharged from Hospital
• The HIV-1 capsid assembly pathway: cellular factors and links to pathogenesis
• The Host Response to Hepatitis C Virus
• The Malaria Control and Elimination Partnership in Africa
• The Malaria Modeling Consortium
• Tissue Regulatory T Cells in Mucosal Infection
• Tissue resident memory response to VZV infection
• TOLLIP Deficiency, Immune Dysfunction, and Tuberculosis Susceptibility
• Unconventional T cells and TB
• Understanding factors limiting B cell activation following vaccination
• Understanding human exposure to tuberculosis and related diseases
• Understanding the differentiation of B cells following vaccination
• University of Washington Arboviral Research Network (UWARN)
• Urethral microbiome and non-gonococcal urethritis in men who have sex with men (MSM)
• Using single cell systems biology to evaluate the role of prior infection in vaccine-induced protection
• Using whole genome sequencing to discover host genetic influences on HIV control and disease
• UW Center for AIDS Research: Humoral Immunology Subcore
• UW Center for AIDS Research: Implementation Science Working Group
• V-OLA: Point-of-care HIV Viral Load Monitoring and Drug Resistance Testing
• Vijana-SMART (Social Media for Adolescent Retention in Treatment) and mPACT (Mobile solutions for the Pediatric to Adult Care Transition)
• Viral Hepatitis in Japan
• Voices of African Immigrants regarding Covid‐19 in King County: Identifying barriers and opportunities for economic recovery
• Women and HIV: Translation of Research into Practice
• Zika in Brazil in Real Time