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Dengue antigen design for a safe effective vaccine

The focus is to design a set of antigens that drive the immune response in such a way that severe secondary disease of Dengue is avoided. Severe secondary infection disease is driven by a failed antibody response in part due to the ineffectual nature of the immuno dominant epitope. The goal of this project is to develop a set of antigens the drives the immune response towards those epitopes that are highly naturalizing and thus potentially avoid severe secondary disease.

Active Dates 
10/01/2021 to 11/30/2023
Faculty Involved