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Optimizing HCV Treatment for Kenyan Persons Who Inject Drugs to Achieve Micro-Elimination

This study will identify approaches to maximize HCV treatment adherence and sustained viral response 12-weeks after treatment completion (SVR-12). It will take place in Nairobi, Kenya and participants will be recruited from needle-syringe programs (NSPs) and opiate substitution programs (OSPs). Using an observational cohort, we will investigate whether treatment success differs between directly observed therapy conducted at NSP sites versus methadone clinics. Nested within this cohort, we will also conduct a cost analysis to identify the cost of providing HCV treatment and to identify drivers of cost. We will follow all study subjects for 1-year to determine the rate of reinfection and changes in liver disease.

Active Dates 
10/01/2018 to 01/31/2021
Faculty Involved 
Health Topics