Discover our impact all over the world.

Numbers displayed on the map are a representation of the activity in each country. Once you use the filter selections below, you will have the opportunity to explore projects and faculty in each country.

Projects + Faculty = Activity Number

##

Overview

Projects 285
Countries 141
Faculty 357
Health Topics 122

Filter from the selections below

Clear All Filters
Back to search

Expansion and targeted maturation of germline HIV-1 bNAb-associated BCRs

The objective of this grant is to investigate the relationship between the relative frequencies of target B cells and the binding affinity of the immunogen with the expansion and maturation of the target B cells in polyclonal immune system in vivo. In this grant, we are investigating a new immunization concept that is based on the utilization of anti-idiotypic antibodies against the germline form of targeted BCRs as tools to specifically expand naïve B cells that express such BCRs, focusing on VRC01-class BCRs.

Active Dates 
01/01/2019 to 12/31/2024
Faculty Involved 
Health Topics