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Role of the microbiome in HIV vaccine induced heterogeneity

The incredible diversity and abundance of the human microbiome has only come to light in the last decade. The scientific community has learned that the gut microbial ecosystem has a major role in the development and homeostasis of the immune system. Our team wants to learn how these systems communicate to shape HIV vaccine immune responses. We are interested in how the microbiome shapes immune responses to HIV vaccines and contributes to vaccine response heterogeneity.