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Biological Determinants of Natural History of AIDS-Defining Cancers

This project examines how host and viral factors impact the response to therapy among persons with HIV-associated cancers in Africa. We will study how the genetic diversity of viruses that cause cancer affects the natural history of these malignancies, and characterize the evolution of the cellular immune response among patients treated for HIV and cancer in Uganda. This work could lead to novel therapeutic and diagnostic strategies for persons with HIV-associated cancers both in sub-Saharan Africa and the US.

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Active Dates 
08/01/2014 to 08/31/2019
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