• Adjunct Professor, Global Health
  • Professor, Bioengineering (Medicine)
  • Adjunct Professor, Chemistry
  • Adjunct Professor, Oral Health Sciences

Department of Bioengineering
Foege N-530J
1705 NE Pacific Street
Seattle, WA 98195
United States

Phone Number: 
206-543-6126
Email: 
yagerp@uw.edu
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Biography 

Paul Yager Ph.D. is a professor in the Department of Bioengineering at UW. He received his AB in Biochemistry from Princeton in 1975, and PhD in Chemistry from the University of Oregon in 1980. After an NRC Fellowship at the Naval Research Laboratory (1980-1982), he joined the NRL staff as a Research Chemist. He moved to the Center (now Department) of Bioengineering at UW in 1987. Since 1992 his lab has focused primarily on development of microfluidics for the analysis of biological fluids in low-cost point-of-care biomedical diagnostics for the developed and developing worlds. From 2005-2010 a team led by Yager was supported by the Gates Foundation developed a point-of-care system for pathogen identification. Since 2008, activity has focused on developing two-dimensional porous networks for ultra-low-cost instrument-free point-of-care pathogen identification for human diagnosis. Readout is often coupled with cell phones for quantitative analysis and data transmission (support of NIH, NSF, DARPA & DTRA).

Education 
  • PhD (University of Oregon)
  • AB (Princeton University)
Country Affiliations 
Languages 
  • French
Health Topics 
  • Biodefense Infectious Diseases
  • Bioengineering
  • Disease Surveillance
  • HIV/AIDS
  • Infectious Diseases (other than STDs)
  • Influenza
  • Malaria
  • Research
  • Respiratory Disease
  • STDs (other than HIV)
  • Viruses
DGH Centers, Programs and Initiatives and Affiliated Organizations 
Publications 

Microfluidic diagnostic technologies for global public health, Yager, P., Edwards, T., Fu, E., Helton, K., Nelson, K., Tam, M. and Weigl, B., Nature, 442(7101). 412-418 (2006)

Isothermal strand displacement amplification (iSDA): a rapid and sensitive method of nucleic acid amplification for point-of-care diagnosis, Toley, B.J., Covelli, I. Belousov, Y., Ramachandran, S., Kline, E., Scarr, N., Vermeulen, N., Mahoney, W., Lutz, B.R. and Yager, P. Analyst, DOI: 10.1039/C5AN01632K (2015)

One-step purification and concentration of DNA in porous membranes for point-of-care applications, Byrnes, S.A., Bishop, J.D., Lafleur, L.K., Buser, J.R., Lutz, B. and Yager, P., Lab on a Chip, 15: 2647-2659 (2015)

Electromechanical cell lysis using a portable audio device: enabling challenging sample preparation at the point-of-care, Buser, J.F., Wollen, A., Heiniger, E.K., Byrnes, S., Kauffman, P.C., Ladd, P.D. and Yager, P., Lab on a Chip, 15(9): 1994-1997 (2015)

A rapid, instrument-free, sample-to-result nucleic acid amplification test, Lafleur, L.K., Bishop, J.D., Heiniger, E.K., Gallagher, R.P., Wheeler, M.D., Kauffman, P., Kline, E.C., Zhang, X.H., Buser, J.R., Kumar, S., Byrnes, S.A., Vermeulen, N.M.J., Scarr, N.K., Belousov, Y., Mahoney, W., Toley, B.J., Ladd, P.D., Barry R Lutz, B.R. and Yager, P., Lab on a Chip, DOI: 10.1039/C6LC00677A, (2016)