• Adjunct Professor, Global Health
  • Professor, Bioengineering
  • Adjunct Professor, Chemistry
  • Adjunct Professor, Oral Health Sciences

Department of Bioengineering
Foege N-530J
1705 NE Pacific Street
Seattle, WA 98195
United States

Phone Number: 
206-543-8063
Email: 
yagerp@uw.edu
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Biography 

Paul Yager, a native of Manhattan, received his A.B. in Biochemistry from Princeton in 1975, and a Ph.D. in Chemistry from the University of Oregon in 1980, specializing in vibrational spectroscopy of biomolecules. After an NRC Fellowship at the Naval Research Laboratory from (1980-1982), he joined the NRL staff as a Research Chemist. He moved to the Center (now Department) of Bioengineering at the University of Washington as Associate Professor in 1987, advancing to Professor in 1995; he served as Chair of the department from 2007 to 2013. Since 1992, his lab has focused primarily on development of microfluidics for the analysis of biological fluids for use in low-cost point-of-care biomedical diagnostics for the developed and developing worlds. From 2005-2010 a team led by Yager was supported by the Bill & Melinda Gates Foundation to develop a low-cost rugged point-of-care system for pathogen identification. Since 2008, most lab activity has focused on developing two-dimensional porous networks for ultra-low-cost instrument-free diagnostics, to be coupled with cell phones for quantitative readout; this has been under support of NIH and DARPA. He has authored >200 research publications, and has over 35 issued patents. For more information, please see Dr. Yager's UW faculty profile.

Expertise: research across the spectrum from basic to translational science; design, development, and production of new technologies, products, and software; commercialization, application, and distribution of health technologies, products, and services

Education 
  • PhD (University of Oregon)
  • AB (Princeton University)
Country Affiliations 
Languages 
  • French
Health Topics 
  • Biodefense infectious diseases
  • Bioengineering
  • Disease Surveillance
  • Health Technologies
  • Infectious Diseases
  • Influenza
  • Malaria
  • Viruses
  • Waterborne Diseases
  • Zoonotic Diseases and Animal Health
Affiliated Organizations: 
Publications 

A rapid, instrument-free, sample-to-result nucleic acid amplification test, Lafleur, L.K., Bishop, J.D., Heiniger, E.K., Gallagher, R.P., Wheeler, M.D., Kauffman, P., Kline, E.C., Zhang, X.H., Buser, J.R., Kumar, S., Byrnes, S.A., Vermeulen, N.M.J., Scarr, N.K., Belousov, Y., Mahoney, W., Toley, B.J., Ladd, P.D., Lutz, B.R. and Yager, P., Lab on a Chip, 16: 3777-3787 DOI: 10.1039/C6LC00677A, (2016)

Disposable autonomous device for rapid swab-to-result diagnosis of influenza, Huang, S., Abe, K., Bennett, S., Liang, T., Ladd, P.D., Yokobe, L., Anderson, C.E., Shah, K., Bishop, J., Purfield, M., Kauffman, P.C., Paul, S., Welch, A-E., Strelitz, B., Follmer, K., Pullar, K., Sanchez-Erebia, L., Gerth-Guyette, E., Domingo, G., Klein, E., Englund, J.A., Fu, E., Yager, P. Analytical Chemistry, doi: 10.1021/acs.analchem.6b04801 (2017)

Rapid diagnostic assay for intact influenza virus using a high affinity hemagglutinin binding protein, Anderson, C.E., Holstein, C.A., Strauch, E-M., Bennett, S., Chevalier, A., Nelson, J.W., Fu, E., Baker, D. and Yager, P. Analytical Chemistry, DOI: 10.1021/acs.analchem.7b00769 (2017)

Enabling lateral transport of genomic DNA through porous membranes for point-of-care applications, Byrnes, S.A., Bishop, J.D. and Yager, P. Analytical Methods, DOI: 10.1039/C7AY00293A (2017)

Design of trimeric influenza neutralizing proteins targeting the hemagglutinin receptor binding site, Strauch, E.M., Bernard, S.M., La, D., Bohn, A.J., Lee, P.S., Anderson, C.E., Nieusma, T., Holstein, C.A., Garcia, N.K., Hooper, K.A., Ravichandran, R., Nelson,J.W., Sheffler, W., Bloom, J.D., Lee, K.K., Ward, A.B., Yager, P., Fuller, D.H., Wilson, I.A., and Baker, D., Nature Biotechnology, DOI: 10.1038/nbt.3907 (2017)