- Professor, Global Health
- Professor, Microbiology
- Professor, Medicine - Allergy and Infectious Dis.
- Adjunct Professor, Laboratory Medicine
University of Washington
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Dr. Mullins obtained his Ph.D. in Cell Biology and Biochemistry from the University of Minnesota in 1978. He did postdoctoral work at the California Institute of Technology before becoming Assistant then Associate Professor at the Harvard University School of Public Health. In 1989 he moved to Stanford University as Professor and was Chairman of the Department of Microbiology and Immunology from 1991 until his move to the University of Washington in 1994 where he is on the faculty of the Departments of Microbiology, Medicine, and Laboratory Medicine. He served as Chair of Microbiology from 1997-2002. Dr. Mullins has published more than 360 original articles, reviews and book chapters on the topics of retroviruses and AIDS and has delivered more than 320 invited seminars and symposium presentations.
The Mullins lab uses the techniques of molecular, computational and virus biology to provide basic insights into the HIV-human host relationship in an effort to assist the fight to stop the AIDS pandemic. They use a variety of techniques to understand the implications of HIV's extraordinary genetic diversity for the pathogenesis of AIDS, with the intention of applying this information to the development of more effective therapies and vaccines. These techniques include virology, molecular biological and statistical analysis of nucleotide sequences.
- PhD (University of Minnesota)
- BA (University of South Florida)
- Drug and Vaccine Development
- HIV Transmission
- Host-Pathogen Interactions
- Infectious Diseases
- Molecular Immunology
- Role of Proviral Loci in HIV Latency
- Biological Determinants of Natural History of AIDS-Defining Cancers
- CFAR: Retrovirology and Molecular Data Science Core
- Defining Critical Events in Early HIV Infection: Effects of Alcohol & Early ART
- Defining HIV reservoirs that rebound following suspension of ART
- Ex Vivo Detection and Analysis of Non-inducible Latent Reservoirs
- HIV integration-mediated modulation of immune regulation in HPV-associated cancers
- HIV Vaccine Trials Network (HVTN)
- Impact of Methamphetamine Use on the HIV Nucleome in individuals on Antiretroviral Therapy
- Martin Delaney Cure Collaboratory - Cell and Gene Therapy for HIV Cure
- Modeling the Evolutionary and Public Health Impacts of HIV Adaptation in Response to Vaccination
Shankarappa, R., J. B. Margolick, S. J. Gange, A. G. Rodrigo, D. Upchurch, H. Farzadegan, P. Gupta, C. R. Rinaldo, G. H. Learn, X. He, X. L. Huang and J. I. Mullins (1999). "Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection." J. Virol. 73(12): 10489-10502.
Liu, Y., J. McNevin, J. Cao, H. Zhao, I. Genowati, K. Wong, S. McLaughlin, M. D. McSweyn, K. Diem, C. E. Stevens, J. Maenza, H. He, D. C. Nickle, D. Shriner, S. E. Holte, A. C. Collier, L. Corey, M. J. McElrath and J. I. Mullins (2006). "Selection on the human immunodeficiency virus type 1 proteome following primary infection." J Virol 80(19): 9519-9529.
Deeks, S. G., B. Autran, B. Berkhout, M. Benkirane, S. Cairns, N. Chomont, T. W. Chun, M. Churchill, M. Di Mascio, C. Katlama, A. Lafeuillade, A. Landay, M. Lederman, S. R. Lewin, F. Maldarelli, D. Margolis, M. Markowitz, J. Martinez-Picado, J. I. Mullins, J. Mellors, S. Moreno, U. O'Doherty, S. Palmer, M. C. Penicaud, M. Peterlin, G. Poli, J. P. Routy, C. Rouzioux, G. Silvestri, M. Stevenson, A. Telenti, C. Van Lint, E. Verdin, A. Woolfrey, J. Zaia and F. Barre-Sinoussi (2012). "Towards an HIV cure: a global scientific strategy." Nat Rev Immunol 12(8): 607-614.
Wagner, T. A., S. McLaughlin, K. Garg, C. Y. Cheung, B. B. Larsen, S. Styrchak, H. C. Huang, P. T. Edlefsen, J. I. Mullins and L. M. Frenkel (2014). "HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection." Science 345(6196): 570-573.
Hu, X., A. Valentin, F. Dayton, V. Kulkarni, C. Alicea, M. Rosati, B. Chowdhury, R. Gautam, K. E. Broderick, N. Y. Sardesai, M. A. Martin, J. I. Mullins, G. N. Pavlakis and B. K. Felber (2016). "DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV." J Immunol 197(10): 3999-4013.