• Adjunct Associate Professor, Global Health
  • Associate Professor, Medicine - Allergy and Infectious Dis.
  • Adjunct Associate Professor, Epidemiology

R&T Bldg, 300 9th Ave
Box 359779
Seattle, WA 98104
United States

Phone Number: 
206-543-1407
Email: 
helenchu@uw.edu
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Biography 

Dr. Chu’s research focus is on preventive interventions against influenza, RSV and emerging respiratory viruses, including SARS-CoV-2. Dr. Chu conducts clinical-translational research on large-scale community-based studies of respiratory viruses, with a focus on vaccines, antivirals, and diagnostics and is currently a Multiple Principal Investigator of the Seattle Flu Study, which first identified COVID-19 community transmission in the United States. She is also interested in defining clinical and immune correlates of protection against respiratory viruses and describing mechanisms of maternal-fetal immunity against respiratory viruses.

Her previous work includes describing transmission patterns of RSV, rhinovirus, and human metapneumovirus, the epidemiology and adverse birth outcomes associated with respiratory viral pneumonia in pregnant women, and the kinetics of transplacental RSV antibody transfer and decay in infants. Dr. Chu has also performed clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh.

More information available on her lab website: https://www.chulab.org

Education 
  • MPH (University of Washington)
  • MD (Duke University Medical Center, Durham, NC)
  • BA (Cornell University)
Country Affiliations 
Languages 
  • Mandarin
Health Topics 
  • Child and Adolescent Health (incl. Pediatrics)
  • COVID-19
  • Disease Surveillance
  • Drug and Vaccine Development
  • Epidemiology
  • Infectious Diseases
  • Influenza
  • Maternal Child Health (incl. Reproductive Health)
  • Research
  • Respiratory Disease
  • Viruses
Publications 

Chung E, Chow EJ, Wilcox NC, Burstein R, Brandstetter E, Han PD, Fay K, Pfau B, Adler A, Lacombe K, Lockwood CM, Uyeki TM, Shendure J, Duchin JS, Rieder MJ, Nickerson DA, Boeckh M, Famulare M, Hughes JP, Starita LM, Bedford T, Englund JA, Chu HY. Comparison of Symptoms and RNA Levels in Children and Adults With SARS-CoV-2 Infection in the Community Setting. JAMA Pediatr. 2021 Jun 11. doi: 10.1001/jamapediatrics.2021.2025. Epub ahead of print. PMID: 34115094.

Logue JK, Franko NM, McCulloch DJ, McDonald D, Magedson A, Wolf CR, Chu HY. Sequelae in Adults at 6 Months After COVID-19 Infection. JAMA Netw Open. 2021 Feb 19;4(2):e210830. doi: 10.1001/jamanetworkopen.2021.0830. PMID: 33606031.

Rogers JH, Link AC, McCulloch D, Brandstetter E, Newman KL, Jackson ML, Hughes JP, Englund JA, Boeckh M, Sugg N, Ilcisin M, Sibley TR, Fay K, Lee J, Han P, Truong M, Richardson M, Nickerson DA, Starita LM, Bedford T, Chu HY. Characteristics of COVID-19 in Homeless Shelters : A Community-Based Surveillance Study. Ann Intern Med. 2021 Jan;174(1):42-49. doi: 10.7326/M20-3799. Epub 2020 Sep 15. PMID: 32931328; PMCID: PMC7517131.

Chu HY, Englund JA, Starita LM, Famulare M, Brandstetter E, Nickerson DA, Rieder MJ, Adler A, Lacombe K, Kim AE, Graham C, Logue J, Wolf CR, Heimonen J, McCulloch DJ, Han PD, Sibley TR, Lee J, Ilcisin M, Fay K, Burstein R, Martin B, Lockwood CM, Thompson M, Lutz B, Jackson M, Hughes JP, Boeckh M, Shendure J, Bedford T. Early Detection of Covid-19 through a Citywide Pandemic Surveillance Platform. N Engl J Med. 2020 May 1;. doi: 10.1056/NEJMc2008646. [Epub ahead of print] PubMed PMID: 32356944; PubMed Central PMCID: PMC7206929.

Chu HY, Steinhoff MC, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA. Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh. The Journal of infectious diseases. 2014; 210(10):1582-9.