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Lakshmi Rajagopal

Associate Professor, Pediatrics
Adjunct Associate Professor, Global Health
Adjunct Associate Professor, Microbiology
Contact 

Seattle Children's Research Institute
1900 Ninth Ave
Seattle, WA
98101

206-884-7336

lakshmi.rajagopal@seattlechildrens.org
Education

PhD (Jawaharlal Nehru University)
MSc (Madurai University (India))
BSc (Bangalore University)

Expertise

Bacterial pathogenesis with a focus on Group B Streptococcus and Staphylococcus aureus infections.

Selected Publications 

Whidbey C, Harrell MI, Burnside K, Ngo L, Becraft AK, Iyer LM, Aravind L, Hitti J, Adams Waldorf KM, and Rajagopal L. A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta. J Exp Med 2013;210(6):1265-1281. PMCID: PMC3674703.

Patras KA, Wang NY, Fletcher EM, Cavaco CK, Jimenez A, Garg M, Fierer J, Sheen TR, Rajagopal L, and Doran KS. Group B Streptococcus CovR regulation modulates host immune signaling pathways to promote vaginal colonization. Cell Microbiol 2013;15(7):1154-1167. PMCID: PMC3657335.

Burnside K and Rajagopal L. Regulation of prokaryotic gene expression by eukaryotic-like enzymes. Curr Opin Microbiol 2012;15(2):125-131. PMCID: PMC 3320669.

Burnside K, Lembo A, Harrell MI, Klein JA, Lopez-Guisa J, Siegesmund AM, Torgerson TR, Oukka M, Molina DM, and Rajagopal L. Vaccination With a UV-Irradiated Genetically Attenuated Mutant of Staphylococcus aureus Provides Protection Against Subsequent Systemic Infection. J Infect Dis 2012;206(11):1734-1744. PMCID: PMC3488195.

Burnside K and Rajagopal L. Aspects of eukaryotic-like signaling in Gram-positive cocci: a focus on virulence. Future Microbiol 2011;6(7):747–761. PMCID: PMC3236639.

Burnside K, Lembo A, Harrell MI, Gurney M, Xue L, Binhtran NT, Connelly JE, Jewell KA, Schmidt BZ, de Los Reyes M, Tao WA, Doran KS, and Rajagopal L. Serine/threonine phosphatase Stp1 mediates post-transcriptional regulation of hemolysin, autolysis, and virulence of Group B Streptococcus. J Biol Chem 2011;286(51):44197-44210. PMCID: PMC3243546.