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Projects 304
Countries 145
Faculty 380
Health Topics 123

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Development and Clinical Evaluation of a Lyophilized Thermostable Tuberculosis Vaccine containing Adjuvant

This project sponsored by NIH/NIAID involves formulation development of an oil-in-water emulsion with TLR4 ligand adjuvant together with a recombinant tuberculosis vaccine antigen in a single vial using lyophilization technology for enhanced thermostability, including cGMP manufacturing and clinical evaluation in a Phase 1 trial.

Countries 
Active Dates 
09/01/2014 to 03/01/2020
Faculty Involved