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Defining BCR evolution during Immunization

The goals of this grant are to express, purify and antigenically characterize trimeric gp140 clade C HIV envelope glycoproteins (derived from early HIV-1 infection) and to evaluate their immunogenic properties by serological and deep sequencing analyses. These Env immunogens were not designed to target specific BCRs.

Active Dates 
12/01/2012 to 11/30/2017
Faculty Involved 
Health Topics